Architecture of an object-oriented modeling framework for human occupation

The limitations of the actual theoretical structure of occupational science are discussed emphasizing on its implications when dealing with the stability and sustainability of social systems. By using a literature review focused on the time evolution and disciplinary distribution of the scientific production about human occupation, it is verified the insufficient production leading to the development of models that facilitate quantitative reasoning to support decision making. As an alternative, the architecture of an object-oriented framework is proposed. The framework is presented by using an UML (Unified Modeling Language) class diagram of a generic occupational system, including the class model of each system’s component: attributes and behaviors. Finally, guidelines are given for the use of the models produced with the framework in simulating diverse occupation systems scenarios

Application of an experimental design of D-optimum mixing based on restrictions for the optimization of the pre-painted steel line of a steel producer and marketing company

The inherent need to optimize production processes allows the generation of new knowledge that allows companies to achieve new horizons in terms of efficient management of productive resources, this study allowed to achieve a new advance in the efficiency of the pre-painting process, where the search focused on the maximization of the hardness of the paint on the metallic surface and the minimization of the percentage of solids in the paint, and by means of the application of a D-Optimo experimental design based on restrictions, it was determined that the Process variables: Monomer, Interlacer and Resin have a statistically significant relationship both with the hardness of the paint layer and with the percentage of solids in the paint. The optimum hardness values achieved are above the restriction imposed by the company to maintain the Knoop hardness value above 25, in the same way it was possible to achieve that the percentage of the solids found is below 30%, This being the minimum value desired by the leaders of the process

The Antioxidant Properties of Lavandula multifida Extract Contribute to Its Beneficial Effects in High-Fat Diet-Induced Obesity in Mice

Obesity is a worldwide public health problem whose prevalence rate has increased steadily over the last few years. Therefore, it is urgent to improve the management of obesity and its comorbidities, and plant-based treatments are receiving increasing attention worldwide. In this regard, the present study aimed to investigate a well-characterized extract of Lavandula multifida (LME) in an experimental model of obesity in mice and explore the underlying mechanisms. Interestingly, the daily administration of LME reduced weight gain as well as improved insulin sensitivity and glucose tolerance. Additionally, LME ameliorated the inflammatory state in both liver and adipose tissue by decreasing the expression of various proinflammatory mediators (Il-6, Tnf-a, Il-1b, Jnk-1, Ppara, Pparg, and Ampk) and prevented increased gut permeability by regulating the expression of mucins (Muc-1, Muc-2, and Muc-3) and proteins implicated in epithelial barrier integrity maintenance (Ocln, Tjp1, and Tff-3). In addition, LME showed the ability to reduce oxidative stress by inhibiting nitrite production on macrophages and lipid peroxidation. These results suggest that LME may represent a promising complementary approach for the management of obesity and its comorbidities.Junta de Andalucía (CTS 164), by the Instituto de Salud Carlos III (ISCIII) (PI19.01058)Spanish Ministry of Economy and Competitiveness (AGL2015-67995-C3-3-R)European Commission (FEDER/ERDF). The CIBEREHDInstituto de Salud Carlos II

Uso de las TICs

Introducción Objetivos Evaluación diagnóstica Temario Evaluación final Créditos Referencias Otros recurso

Análisis econométrico de los determinantes del crecimiento industrial en Colombia.

An econometric study is carried out using a panel data model with fixed effects to identify the industrial development determinants in Colombia during the term 2005–2015. The database used in the study corresponds to World Bank and the Colombian state. The determinants of industrial growth identified at the theoretical level that allow the enhancement of productive capacities to face foreign competition in Colombia are: innovation; networks of innovations and knowledge among companies and organizations; the interest rate; the capital-product ratio, the unit labor cost; and the exchange rate. The amount invested in scientific, technological and innovation activities by industrial group is the only variable that is not significant in the model.Se lleva a cabo un estudio econométrico utilizando un modelo de datos de panel con efectos fijos para identificar los determinantes del desarrollo industrial en Colombia durante el período 2005-2015. La base de datos utilizada en el estudio corresponde al Banco Mundial y al estado colombiano. Los determinantes del crecimiento industrial identificados a nivel teórico que permiten el aumento de las capacidades productivas para enfrentar la competencia extranjera en Colombia son: innovación; Redes de innovación y conocimiento entre empresas y organizaciones. la tasa de interés; la relación capital-producto, el coste laboral unitario; y el tipo de cambio. La cantidad invertida en actividades científicas, tecnológicas y de innovación por grupo industrial es la única variable que no es significativa en el modelo

Dinámica del mercado de transporte aéreo de pasajeros en Colombia (2016)

Today, IT professionals are challenged with the task of ongoing improvements to achieve goals of businesses. Unfortunately, some factor/Resources, skill environment does not dynamically grow as fast as business needs. That sequence of events creates major obstacles for DB infrastructure, deployment, administration and maintenance. This paper discusses the performance issues, different bottlenecks such as CPU bottlenecks, Memory structures, Input output capacity issue, Database Design issues and Indexing issues. Also this paper address Tuning stages and how SQL queries can be optimized for better performance. In this paper we are focusing on query tuning tips & tricks which can be applied to gain immediate performance gain by creating Query Execution Flow Chart. We demonstrate the application of this technique in an Employee Biometric Attendance Management SystemHoy en día, los profesionales de TI se enfrentan a la tarea de continuar Mejoras para lograr los objetivos de las empresas. Desafortunadamente, algunos factor / Recursos, el entorno de habilidades no crece dinámicamente tan rápido como Necesidades del negocio. Esa secuencia de eventos crea grandes obstáculos para DB Infraestructura, despliegue, administración y mantenimiento. Este documento analiza los problemas de rendimiento, diferentes cuellos de botella, como cuellos de botella de la CPU, Estructuras de memoria, problema de capacidad de salida de entrada, problemas de diseño de base de datos y Problemas de indexación. También este documento aborda las etapas de ajuste y cómo las consultas SQL Se puede optimizar para un mejor rendimiento. En este artículo nos centramos en la consulta. Consejos y trucos de ajuste que se pueden aplicar para obtener una ganancia de rendimiento inmediata mediante la creación de diagrama de flujo de ejecución de consultas. Demostramos la aplicación de este Técnica en un sistema de gestión de asistencia biométrica para empleados

The Antioxidant Properties of <i>Lavandula multifida</i> Extract Contribute to Its Beneficial Effects in High-Fat Diet-Induced Obesity in Mice

Obesity is a worldwide public health problem whose prevalence rate has increased steadily over the last few years. Therefore, it is urgent to improve the management of obesity and its comorbidities, and plant-based treatments are receiving increasing attention worldwide. In this regard, the present study aimed to investigate a well-characterized extract of Lavandula multifida (LME) in an experimental model of obesity in mice and explore the underlying mechanisms. Interestingly, the daily administration of LME reduced weight gain as well as improved insulin sensitivity and glucose tolerance. Additionally, LME ameliorated the inflammatory state in both liver and adipose tissue by decreasing the expression of various proinflammatory mediators (Il-6, Tnf-α, Il-1β, Jnk-1, Pparα, Pparγ, and Ampk) and prevented increased gut permeability by regulating the expression of mucins (Muc-1, Muc-2, and Muc-3) and proteins implicated in epithelial barrier integrity maintenance (Ocln, Tjp1, and Tff-3). In addition, LME showed the ability to reduce oxidative stress by inhibiting nitrite production on macrophages and lipid peroxidation. These results suggest that LME may represent a promising complementary approach for the management of obesity and its comorbidities